Successful Treatment of Recurrent Atypical Lung Carcinoid Tumor with Photodynamic Therapy: A Case Report
Lung carcinoid tumors are rare neuroendocrine tumors. Traditional treatments like surgery, radiotherapy, and chemotherapy have limited efficacy for some patients (e.g., inoperable or recurrent cases). Photodynamic therapy (PDT), a minimally - invasive and highly - targeted treatment, shows potential in treating lung carcinoid tumors. This article details a pathologically - confirmed case of an atypical lung carcinoid tumor. After surgical resection, the recurrence and metastasis were successfully treated with PDT using intravenous hematoporphyrin. Eleven months post-treatment, bronchoscopy revealed smooth mucosa at the lesion site. The patient showed no signs of recurrence during the 11-month follow-up period, hemoptysis symptoms disappeared, and the patient recovered well with a KPS of 100 and a score of 0 for shortness of breath. This case report indicates that PDT has significant local control and a good safety profile in lung carcinoid tumors.
Authors
- Xiaofeng Liu (ORCID: https://orcid.org/0000-0002-8296-7076)
- Hongwu Wang (ORCID: https://orcid.org/0000-0001-6401-977X)
Institutions
- Beijing University of Chinese Medicine (CN)
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.pdpdt.2025.105046
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00