Study of the efficacy and safety of photodynamic therapy for pigmented nevus using various photosensitizers under the control of fluorescence diagnostics and assessment of tissue hemoglobin oxygenation

Photodynamic therapy in combination with various photosensitizers offers a potential alternative to surgical resection of pigmented nevus, with the advantage of preserving healthy surrounding tissue and preventing keloid scar formation. Photodynamic therapy of pigmented nevus was applied under the control of video and spectral fluorescence diagnostics and spectroscopic evaluation of hemoglobin oxygenation in tissues. The treatment of pigmented nevus resulted in the regression of the skin lesion area, without the formation of keloid scar tissue. Photodynamic therapy has been demonstrated to be a safe and effective treatment for pigmented nevus, ensuring precise exposure to the pathologic tissue without damaging the healthy tissue.