Plant-derived extracellular vesicles: emerging carriers for ingestible nucleotide delivery
This review introduces recent advancements of PEV-based technologies focused on ingestible nucleotide delivery, not only contributing valuable theoretical insights but also offering practical guidance for future precision medicine and drug development by PEVs. However, the current existence of regulatory ambiguity and low production efficiency has hindered the clinical translation and large-scale application of PEV-based oral nucleotide delivery systems.
Authors
- Zhen‐Chao Dong (ORCID: https://orcid.org/0000-0002-4596-6269)
- Guangyu Fan
- Jung Seung Lee (ORCID: https://orcid.org/0000-0002-7722-0461)
- Yifan Feng (ORCID: https://orcid.org/0000-0002-4291-6493)
- Meilin Zhu (ORCID: https://orcid.org/0000-0001-8719-8934)
- Xin Li (ORCID: https://orcid.org/0000-0002-7837-7874)
- Ying Li (ORCID: https://orcid.org/0000-0003-2700-4768)
- Jixiang Zhao (ORCID: https://orcid.org/0000-0001-7663-0568)
- Z. Li (ORCID: https://orcid.org/0000-0002-1232-2803)
- Wei Jin (ORCID: https://orcid.org/0000-0002-2905-2109)
- Yang Lu
Institutions
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Harbin University of Commerce (CN)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Expert Opinion on Drug Delivery
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1080/17425247.2025.2591237
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81