Prognostic utility of procalcitonin and lactate clearance for in-hospital mortality in sepsis
Lactate clearance with 10% cutoff is a better predictor of in-hospital mortality in patients presenting to the ED with sepsis or septic shock compared to PCTc. An optimal PCTc cutoff of 23.1% was identified; however, it did not reach statistical significance for survival. Future prospective studies are needed to better define optimal biomarker cutoffs and compare their predictive accuracy for in-hospital mortality.
Authors
- Hani Tamim (ORCID: https://orcid.org/0000-0002-2019-4362)
- Rafik Diab
- Maha Makki (ORCID: https://orcid.org/0000-0003-4559-0457)
- Ralphe Bou Chebl
- Nour Barmo (ORCID: https://orcid.org/0000-0002-3264-8077)
- Gilbert Abou Dagher (ORCID: https://orcid.org/0000-0002-9147-1515)
- Reem Siblini
Institutions
- Alfaisal University (SA)
- American University of Beirut Medical Center (LB)
- American University of Beirut (LB)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3389/fmed.2025.1679297
- Citations
- 2
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71