Gene and protein profiling of Dickkopf-3 and complement factor H in periodontitis and coronary artery disease
The study found elevated DKK-3 (rs11544817) and reduced CFH (rs10737680) protein levels and gene expression in patients with periodontitis and CAD, suggesting that these genes regulate their respective proteins.
Authors
- Prabhu Manickam Natarajan (ORCID: https://orcid.org/0000-0002-4780-0465)
- Jaideep Mahendra
- M. A. Arumugam
- Bawatharani Maharavi
Institutions
- Government Kilpauk Medical College (IN)
- Ajman University (AE)
- Meenakshi Ammal Dental College and Hospital (IN)
Publication Details
- Journal
- Frontiers in Dental Medicine
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3389/fdmed.2025.1679757
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00