Genomic dissection of the antimicrobial resistance epidemiology of Salmonella Typhimurium
This large-scale genomic analysis highlights substantial diversity in AMR patterns among STm genomic types globally. The identification of recently emerged cefotaxime resistant and ciprofloxacin intermediate STs underscores the continued threat of resistance to antibiotics critical for treatment of severe salmonellosis. Integration of MGT strain typing with AMR prediction provides scalable, sharable, standardised and precise tracking of resistant isolates/STs, offering a powerful framework for global AMR surveillance.
Authors
- Sandeep Kaur (ORCID: https://orcid.org/0000-0003-0356-3151)
- Ruiting Lan (ORCID: https://orcid.org/0000-0001-9834-5258)
- Michael Payne (ORCID: https://orcid.org/0000-0003-1911-7033)
- Sally R. Partridge (ORCID: https://orcid.org/0000-0002-0666-8330)
- Vitali Sintchenko (ORCID: https://orcid.org/0000-0002-9261-3650)
Institutions
- The University of Sydney (AU)
- Taronga Conservation Society Australia (AU)
- Westmead Hospital (AU)
- UNSW Sydney (AU)
- Westmead Institute (AU)
- Westmead Institute for Medical Research (AU)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3389/fmicb.2025.1683995
- Primary Topic
- Salmonella and Campylobacter epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of New South Wales
- Medical Research Council
- National Health and Medical Research Council