Developing scalable woven textile-based scaffolds for tubular tissues with Core–Sheath nanofibre yarns and tuneable weave architectures
This approach overcomes key limitations of traditional electrospun membranes and manual weaving methods by offering reproducibility, structural stability, and design flexibility. Our results demonstrate that controlling yarn morphology and mesoscopic weave architecture can guide cell behaviour and tissue organisation, providing a promising platform for engineering vascular, tracheal, and oesophageal grafts with clinically relevant properties.
Authors
- Luis Larrea Murillo (ORCID: https://orcid.org/0000-0001-5634-7300)
- Olga Tsigkou (ORCID: https://orcid.org/0000-0002-5250-8610)
- Celina Jones (ORCID: https://orcid.org/0000-0002-1824-7234)
- Anna Doersam (ORCID: https://orcid.org/0000-0003-4267-1980)
Institutions
- Manchester Metropolitan University (GB)
- University of Manchester (GB)
- Henry Royce Institute (GB)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3389/fbioe.2025.1655852
- Primary Topic
- Electrospun Nanofibers in Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Engineering and Physical Sciences Research Council