Pulsed electric fields: a sharp sword in the battle against cancers

Cancer remains a significant threat to human health, and conventional treatments such as surgery, chemotherapy, and radiotherapy have their limitations. In recent years, pulsed electric fields (PEFs) has garnered attention as an emerging method for cancer treatment. It primarily utilizes high-intensity pulse electric fields applied to tumor cells, inducing effects such as electroporation or internal electrical processing, which lead to cell death. This review will introduce the principles of PEFs, its application fields, and its prospects in cancer treatment, aiming to provide readers with a comprehensive understanding of the research areas related to PEFs and cancer therapy.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-11-20
DOI
https://doi.org/10.3389/fimmu.2025.1682539
Primary Topic
Microbial Inactivation Methods
Type
article
Field-Weighted Citation Impact
0.00
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article

Pulsed electric fields: a sharp sword in the battle against cancers

Fei Teng, Shoulong Dong, Liang Yu, Chenguo Yao et al.
Frontiers in Immunology
Microbial Inactivation Methods
article

Pulsed electric fields: a sharp sword in the battle against cancers

Fei Teng, Shoulong Dong, Liang Yu, Chenguo Yao, Yuan Wang, Lu Zhang, Zhiqiang Wang, Wei Xu, Yang Chen
article en

Abstract

Cancer remains a significant threat to human health, and conventional treatments such as surgery, chemotherapy, and radiotherapy have their limitations. In recent years, pulsed electric fields (PEFs) has garnered attention as an emerging method for cancer treatment. It primarily utilizes high-intensity pulse electric fields applied to tumor cells, inducing effects such as electroporation or internal electrical processing, which lead to cell death. This review will introduce the principles of PEFs, its application fields, and its prospects in cancer treatment, aiming to provide readers with a comprehensive understanding of the research areas related to PEFs and cancer therapy.

Frontiers in ImmunologyVol. 16
Chongqing University (CN), Chongqing Cancer Hospital (CN)
Openalex Percentile: Top 63%
Microbial Inactivation Methods
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