Reversible splenial lesion syndrome associated with Graves’ disease and hepatic dysfunction: a case report
This study presents a case of a patient with RESLES characterized by Graves' disease and liver function abnormalities, who was sensitive to anti-thyroid drug (methimazole) and hormone therapy (methylprednisolone sodium succinate) and had a favorable prognosis. This study contributed to expanding the clinical understanding of RESLES and suggests that, in clinical practice, autoimmune hyperthyroidism may be a novel trigger for RESLES, while concurrent liver dysfunction in this context requires further investigation.
Authors
- Tianyu Zhong (ORCID: https://orcid.org/0000-0003-1934-0032)
- Jianping Lv
- Heng Liu (ORCID: https://orcid.org/0000-0002-0456-4626)
- Jing Chen (ORCID: https://orcid.org/0000-0003-2434-0010)
- Yanhong Zhang (ORCID: https://orcid.org/0000-0002-3051-1130)
- Xue Wang (ORCID: https://orcid.org/0000-0002-6298-1858)
- Min Li (ORCID: https://orcid.org/0000-0002-5035-1672)
- Yi‐Jia Lin
- Xinyi Wu
- Xingchen He (ORCID: https://orcid.org/0000-0003-4314-0663)
- Xuchu Weng
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Guangzhou University (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3389/fnins.2025.1691469
- Primary Topic
- Infectious Encephalopathies and Encephalitis
- Type
- article
- Field-Weighted Citation Impact
- 0.00