Increased abundance of actinobacteria and upregulation of primary bile acid biosynthesis in diabetic foot ulcers
DF is associated with distinct alterations in arterial microbiota composition and metabolic pathways. Alterations in Actinobacteria and primary bile acid biosynthesis may be relevant to DF progression and could serve as potential therapeutic targets.
Authors
- Mi Zhou (ORCID: https://orcid.org/0000-0001-7626-9768)
- Tianshu Wei
- Xiaojun Zhou (ORCID: https://orcid.org/0000-0002-6367-696X)
- Rui Zhang (ORCID: https://orcid.org/0000-0001-7879-6131)
- Han Zhang (ORCID: https://orcid.org/0000-0002-5608-9185)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Shandong University (CN)
- Peking University (CN)
- Discovery Institute (US)
- Beijing Jishuitan Hospital (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Qilu Hospital of Shandong University (CN)
- Shandong First Medical University (CN)
- Monash University (AU)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3389/fcimb.2025.1651828
- Primary Topic
- Diabetic Foot Ulcer Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- China Scholarship Council