Abnormal gray matter volume and structural covariance network of basal ganglia-limbic system in patients with major depression disorder

Our findings suggest the pathophysiology of MDD may primarily lie in the abnormal morphology and interregional coordinated development of the basal ganglia-limbic system. The current results provided novel supplementary evidence for the hypothesis of structural aberrations in MDD.

Authors

Institutions

Publication Details

Journal
Frontiers in Neurology
Published
2025-11-20
DOI
https://doi.org/10.3389/fneur.2025.1712229
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Abnormal gray matter volume and structural covariance network of basal ganglia-limbic system in patients with major depression disorder

Ruiping Zheng, Shaoqiang Han, Yong Zhang, Yuan Chen
Frontiers in Neurology
Functional Brain Connectivity Studies
article

Abnormal gray matter volume and structural covariance network of basal ganglia-limbic system in patients with major depression disorder

Ruiping Zheng, Shaoqiang Han, Yong Zhang, Yuan Chen
article en

Abstract

Our findings suggest the pathophysiology of MDD may primarily lie in the abnormal morphology and interregional coordinated development of the basal ganglia-limbic system. The current results provided novel supplementary evidence for the hypothesis of structural aberrations in MDD.

Frontiers in NeurologyVol. 16
First Affiliated Hospital of Zhengzhou University (CN)
Openalex Percentile: Top 65%
Functional Brain Connectivity Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.