Serum metabolites with diagnostic potential in prostate cancer and the inhibitory effects of alpha-Tocomonoenol on prostate cancer cells
This study demonstrates that serum metabolites have the potential to serve as diagnostic biomarkers for the early detection of prostate cancer. Furthermore, alpha-Tocomonoenol might exert an anti-proliferative effect on prostate cancer cells through binding to androgen receptors, providing new insights into the development of novel diagnostic tools and therapeutic strategies for prostate cancer.
Authors
- Chun Yang (ORCID: https://orcid.org/0000-0002-1979-0335)
- Xiang Zhang (ORCID: https://orcid.org/0000-0001-6047-0934)
- Bo Liu (ORCID: https://orcid.org/0000-0002-2393-117X)
- Ninghan Feng (ORCID: https://orcid.org/0009-0006-7425-8751)
- Yang Shen (ORCID: https://orcid.org/0000-0001-6607-7818)
- Yuhua Zhou (ORCID: https://orcid.org/0009-0005-4490-804X)
- Jing Lv
- Yuwei Zhang (ORCID: https://orcid.org/0009-0008-1016-7361)
Institutions
- Jiangnan University (CN)
- Nantong University (CN)
- Wuxi People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3389/fonc.2025.1691767
- Primary Topic
- Phytochemical Studies and Bioactivities
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province