Exploring the characteristics of gut microbiota in the development and progression of early-stage colorectal cancer based on metagenomic sequencing
Gut microbiota profiles varied significantly among HC, polyp, SCRA, LCRA, and IMC groups. Specific microbial signatures were able to effectively differentiate IMC from both HC and non-malignant colorectal lesions, highlighting their potential as diagnostic biomarkers.
Authors
- Jie Lv
- Lu Yang (ORCID: https://orcid.org/0000-0003-2176-7684)
- Zhijie Yang (ORCID: https://orcid.org/0000-0003-3833-0809)
- Xu Wang (ORCID: https://orcid.org/0000-0003-1094-1843)
- Qianqian Chen (ORCID: https://orcid.org/0009-0006-9078-5711)
- Jianhua Xu
- Bin Sun (ORCID: https://orcid.org/0000-0002-6244-8666)
- Jing Guan (ORCID: https://orcid.org/0000-0002-4978-2512)
- Gerald Gui
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3389/fmicb.2025.1658160
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00