Long-term survival after solitary ocular metastasis following radical resection of esophagogastric junction carcinoma: a rare case report

This case highlights that integrated multimodal therapy-including systemic and local interventions-can result in long-term survival for patients with isolated ocular metastasis from EGJ cancer. MDT-based, individualized treatment planning is essential for optimizing outcomes in rare metastatic scenarios and may inform future precision oncology approaches.

Authors

Yihai Zhai
Yunyi Du (ORCID: https://orcid.org/0000-0002-0830-0708)
Ning Ma (ORCID: https://orcid.org/0000-0003-2833-5331)
Xiaoling Zhang (ORCID: https://orcid.org/0000-0001-5789-9676)
Jun Zhao (ORCID: https://orcid.org/0000-0002-8094-9229)
Yangjun Gao (ORCID: https://orcid.org/0009-0005-3064-6923)

Institutions

Changzhi Medical College (CN)

Publication Details

Journal: Frontiers in Oncology
Published: 2025-11-20
DOI: https://doi.org/10.3389/fonc.2025.1650111
Primary Topic: Ocular Oncology and Treatments
Type: article
Field-Weighted Citation Impact: 0.00

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article

Long-term survival after solitary ocular metastasis following radical resection of esophagogastric junction carcinoma: a rare case report

Yihai Zhai, Yunyi Du, Ning Ma, Xiaoling Zhang et al.

Nov 20, 2025

Frontiers in Oncology

Ocular Oncology and Treatments

article

Long-term survival after solitary ocular metastasis following radical resection of esophagogastric junction carcinoma: a rare case report

Yihai Zhai, Yunyi Du, Ning Ma, Xiaoling Zhang, Jun Zhao, Yangjun Gao

November 20, 2025article en

Abstract

This case highlights that integrated multimodal therapy-including systemic and local interventions-can result in long-term survival for patients with isolated ocular metastasis from EGJ cancer. MDT-based, individualized treatment planning is essential for optimizing outcomes in rare metastatic scenarios and may inform future precision oncology approaches.

Frontiers in OncologyVol. 15

Changzhi Medical College (CN)

Openalex Percentile: Top 51%

Ocular Oncology and Treatments

DOI Open Access PDF OpenAlex

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Long-term survival after solitary ocular metastasis following radical resection of esophagogastric junction carcinoma: a rare case report — Yihai Zhai, Yunyi Du, et al. · Frontiers in Oncology (2025) | TGRS Research Map | TGRS