Pan-cancer analysis reveals ELFN1 as a novel prognostic biomarker and immunotherapeutic target associated with tumor microenvironment remodeling and promoting malignant phenotypes in colorectal cancer
The expression level of ELFN1 may provide insights into tumor development and progression in multiple cancers, including CRC, highlighting its potential utility as an effective prognostic biomarkers and immunotherapeutic targets.
Authors
- Wei Yan
- Fujin Liu (ORCID: https://orcid.org/0009-0007-4605-2630)
- Shasha Hu (ORCID: https://orcid.org/0000-0002-0646-0601)
- Bo Wang (ORCID: https://orcid.org/0000-0003-3042-769X)
- Yu Wu (ORCID: https://orcid.org/0009-0008-9561-9821)
- Tianyuan Tan
- Xin-Nian Li
Institutions
- Hainan General Hospital (CN)
- Southern Medical University (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3389/fonc.2025.1583277
- Primary Topic
- Wnt/β-catenin signaling in development and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00