A unified catalog of 14,062 microbial species reference genomes provides new insight into the gut microbiota in high-altitude mammals
Our results showed that animals living in harsh environments are promising sources for the discovery of novel biological functions of gut residing microbes. The results of this study provide insight into the diversity and functionality of the gut microbiota in large herbivores living at QTP as well as the diverse evolutionary patterns of host-gut microbiota interaction over evolutionary times. Video Abstract.
Authors
- Han Gao (ORCID: https://orcid.org/0000-0002-3990-3624)
- Liang Xiao (ORCID: https://orcid.org/0000-0003-0836-4397)
- Karsten Kristiansen (ORCID: https://orcid.org/0000-0002-6024-0917)
- Jianan Sang
- Xingwei Shi (ORCID: https://orcid.org/0000-0002-4037-9823)
- Hong Zhou (ORCID: https://orcid.org/0000-0003-0120-3347)
- Libing Bai
- C. Tian (ORCID: https://orcid.org/0009-0000-8972-3907)
- Min Dai (ORCID: https://orcid.org/0000-0003-1631-0778)
- Yu Luo (ORCID: https://orcid.org/0000-0002-3834-498X)
- Jiangkun Yu (ORCID: https://orcid.org/0000-0002-1832-7832)
- Daohua Zhuang
- Fangfang Zhao (ORCID: https://orcid.org/0000-0001-8242-5069)
- Huan Liu (ORCID: https://orcid.org/0000-0003-3909-0931)
- Xiaotong Liu (ORCID: https://orcid.org/0000-0002-9164-5642)
- Jian Wang (ORCID: https://orcid.org/0000-0003-4949-4753)
- Zhigang Zhang (ORCID: https://orcid.org/0000-0001-8965-223X)
- Xiaoping Li (ORCID: https://orcid.org/0000-0002-6339-0507)
- Teng Li (ORCID: https://orcid.org/0000-0002-3224-0477)
- Xun Xu (ORCID: https://orcid.org/0000-0002-5338-5173)
- Tao Zhang (ORCID: https://orcid.org/0000-0002-2436-2298)
- Liu Tian (ORCID: https://orcid.org/0000-0002-4421-5105)
- Lei Zhu (ORCID: https://orcid.org/0009-0004-3602-1281)
- Qunfu Wu (ORCID: https://orcid.org/0009-0006-3088-0119)
- Zecheng Tang (ORCID: https://orcid.org/0009-0000-4747-2468)
Institutions
- BGI Group (China) (CN)
- University of Copenhagen (DK)
- Yunnan University (CN)
- Qingdao Center of Resource Chemistry and New Materials (CN)
- BGI Research (CN)
- IT University of Copenhagen (DK)
Publication Details
- Journal
- Microbiome
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1186/s40168-025-02232-5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Yunnan University
- Science and Technology Department of Tibet