Multi-omics analysis reveals PIAS family gene dysregulation as a driver of head and neck squamous cell carcinoma (HNSC) progression and therapeutic vulnerability
These findings contribute to the understanding of PIAS family genes in HNSC pathogenesis, diagnosis, prognosis, and potential therapeutic targeting.
Authors
- Saeedah Musaed Almutairi
- Afshan Syed Abbas (ORCID: https://orcid.org/0000-0002-1062-6918)
- Taghreed N. Almanaa (ORCID: https://orcid.org/0000-0002-1353-789X)
- Syeda Amber Hameed (ORCID: https://orcid.org/0000-0002-3950-7883)
- Muhammad Ayaz (ORCID: https://orcid.org/0000-0002-7301-7386)
- Mehreen Ishfaq (ORCID: https://orcid.org/0000-0002-9744-6126)
- Qurat ul Ain
- Abdulaziz Alamri (ORCID: https://orcid.org/0009-0002-3942-5455)
- Mumtaz Hussain
- Mostafa A. Abdel-Maksoud
- Yasir Hameed
- Mujeeb ur Rehman Bhanbhro
Institutions
- Tokyo University of Science (JP)
- Islamia University of Bahawalpur (PK)
- Bahawal Victoria Hospital (PK)
- King Saud University (SA)
- MRC Unit the Gambia (GM)
- National Institute of Health (PK)
- University of Education (PK)
- Quaid-e-Awam University of Engineering, Science and Technology (PK)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1007/s12672-025-04100-y
- Citations
- 2
- Primary Topic
- Protease and Inhibitor Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.87