CSF pTDP-43 across the Alzheimer's spectrum: Links to amyloid, APOE and vasculopathy
CSF pTDP-43 measured by ELISA cannot distinguish between MCI, AD, and VaD. However, it may reflect hippocampal pTDP-43 burden and is associated with some vascular and Aβ-related changes.
Authors
- Dovilė Pocevičiūtė
- Oskar Hansson (ORCID: https://orcid.org/0000-0001-8467-7286)
- Jessica Santiago (ORCID: https://orcid.org/0009-0000-9772-7510)
- Remi Mahmoud (ORCID: https://orcid.org/0000-0002-4138-3058)
- Shorena Janelidze (ORCID: https://orcid.org/0000-0003-2869-8378)
- Zeinab Rafiee
- Malin Wennström (ORCID: https://orcid.org/0000-0002-9957-1801)
Institutions
- Malmö University (SE)
- Lund University (SE)
Publication Details
- Journal
- Neurobiology of Disease
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.nbd.2025.107193
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00