Attenuating α-synuclein pathology in mice with in situ engineered astrocytes
CAR-A-based strategy is an effective treatment for PD-like mouse model. This in situ CAR-A technology provides an innovative and feasible strategy to treat PD and other brain disorders.
Authors
- Xiaoyu Du (ORCID: https://orcid.org/0000-0002-4641-1994)
- Jie Zhu (ORCID: https://orcid.org/0000-0001-5304-7708)
- Haohan Zhang (ORCID: https://orcid.org/0009-0003-0616-5455)
- Rui‐tian Liu (ORCID: https://orcid.org/0000-0002-4297-4765)
- Shiyu Liang (ORCID: https://orcid.org/0009-0002-0261-3727)
- Fang Cui (ORCID: https://orcid.org/0000-0003-4487-8790)
- Xiaolin Yu (ORCID: https://orcid.org/0000-0003-3256-0638)
- Minghan Jiao (ORCID: https://orcid.org/0009-0005-3096-6142)
- Yaru Huang (ORCID: https://orcid.org/0000-0002-5650-2240)
- Fei Chen (ORCID: https://orcid.org/0000-0002-6897-2725)
- Lun Zhang (ORCID: https://orcid.org/0000-0003-1936-3971)
- Shuai Lü (ORCID: https://orcid.org/0000-0002-0169-349X)
- Jing Zhou (ORCID: https://orcid.org/0000-0002-9167-0530)
Institutions
- Ningxia University (CN)
- China Rehabilitation Research Center (CN)
- Institute of Process Engineering (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Translational Neurodegeneration
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1186/s40035-025-00518-0
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39