Dietary glycyrrhizin enhances reproductive performance by improving intestinal microbiota, liver lipid metabolism and ovarian senescence in aged breeder hens
These results collectively demonstrate that dietary supplementation with 100 mg/kg GL improved reproductive performance by reversing age-induced changes in gut microbiota, enhancing hepatic vitellogenin synthesis, and ameliorating ovarian function in aged breeder hens. This study suggests that dietary GL is a potential strategy to improve reproductive performance in broiler breeder hens during the late laying period.
Authors
- Guangju Wang (ORCID: https://orcid.org/0000-0002-8852-8429)
- Yun Shi (ORCID: https://orcid.org/0000-0001-7627-1155)
- Huchuan Liu
- Huiyao Ge (ORCID: https://orcid.org/0000-0002-4928-1777)
- Chunmei Li (ORCID: https://orcid.org/0000-0002-6158-1254)
- Zhenwu Huang (ORCID: https://orcid.org/0000-0002-6997-2612)
- Jinghai Feng
- Minhong Zhang
Institutions
- Nanjing Agricultural University (CN)
- Chinese Academy of Agricultural Sciences (CN)
- Qingdao Institute of Animal Husbandry and Veterinary Medicine (CN)
- Institute of Animal Sciences (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1186/s40104-025-01288-5
- Citations
- 1
- Primary Topic
- Animal Nutrition and Physiology
- Type
- article
- Field-Weighted Citation Impact
- 1.19
Funders
- Chinese Academy of Agricultural Sciences
- National Key Research and Development Program of China
- Agricultural Science and Technology Innovation Program