The location of a translocation breakpoint, rather than fragment size, is associated with spermatogenic function
Genetic counseling for male translocation carriers should prioritize breakpoint location, particularly on 1q, over fragment size when evaluating spermatogenic impairment risk.
Authors
- Yitong Zheng (ORCID: https://orcid.org/0009-0000-3143-0802)
- Y. L. Hao (ORCID: https://orcid.org/0009-0008-0419-7986)
- Jin Huang (ORCID: https://orcid.org/0000-0003-1879-4219)
- Yun Wang (ORCID: https://orcid.org/0000-0002-4357-8166)
- Minjie Shao
- Liang Chang (ORCID: https://orcid.org/0000-0001-7220-0544)
- Yapeng Wang (ORCID: https://orcid.org/0000-0002-2923-1406)
- Yong Han (ORCID: https://orcid.org/0000-0002-2885-2921)
Institutions
- Peking University (CN)
- Reproductive Science Center (US)
- Ministry of Education (RO)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Reproduction Fertility and Development
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1071/rd25125
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00