What is debridement, antibiotics, and implant retention in orthopaedic oncology?

The study highlights global inconsistencies in DAIR practices for PJI in orthopaedic oncology, with financial disparities impacting modular component exchange. Standardized definitions are lacking, and we propose that if only polyethylene is changed, then the procedure is referred to as 'poly exchange'; we recommend defining the procedure as DAIR when extensive debridement, lavage, and removal, wash, and reimplanting of all modular components is done while retaining stable stems, followed by suppressive antibiotic therapy; and finally, we recommend that if all the modular components are changed for new ones, the procedure is referred to as 'DAIR plus'.

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Publication Details

Journal
Bone & Joint Open
Published
2025-11-20
DOI
https://doi.org/10.1302/2633-1462.611.bjo-2025-0114.r2
Citations
1
Primary Topic
Management of metastatic bone disease
Type
article
Field-Weighted Citation Impact
2.01
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article

What is debridement, antibiotics, and implant retention in orthopaedic oncology?

Santiago A. Lozano‐Calderón, Lee Jeys, Vineet Kurisunkal, Minna Laitinen et al.
1 citations
Bone & Joint Open
Management of metastatic bone disease
2.01
article

What is debridement, antibiotics, and implant retention in orthopaedic oncology?

Santiago A. Lozano‐Calderón, Lee Jeys, Vineet Kurisunkal, Minna Laitinen, Ashish Gulia, Zainab Aqeel Khan, Zeeshan Khan, Tomas Zamorra
article en
1 citations

Abstract

The study highlights global inconsistencies in DAIR practices for PJI in orthopaedic oncology, with financial disparities impacting modular component exchange. Standardized definitions are lacking, and we propose that if only polyethylene is changed, then the procedure is referred to as 'poly exchange'; we recommend defining the procedure as DAIR when extensive debridement, lavage, and removal, wash, and reimplanting of all modular components is done while retaining stable stems, followed by suppressive antibiotic therapy; and finally, we recommend that if all the modular components are changed for new ones, the procedure is referred to as 'DAIR plus'.

Bone & Joint OpenVol. 6(11)
Khyber Medical College (PK), Pontificia Universidad Católica de Chile (CL), Bhabha Hospital (IN), Helsinki University Hospital (FI), Royal Orthopaedic Hospital (GB), Massachusetts General Hospital (US), Cancer Hospital and Research Institute (IN), Pharmo Institute (NL)
Openalex Percentile: Top 10%
Management of metastatic bone disease
2.01
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What is debridement, antibiotics, and implant retention in orthopaedic oncology? — Santiago A. Lozano‐Calderón, Lee Jeys, et al. · Bone & Joint Open (2025) | TGRS Research Map | TGRS