Teratoma-free cartilage regeneration using <i>p21</i> −/− iPSCs engineered with iCasp9

These findings suggest that iCasp9-mediated elimination of iPSCs can effectively mitigate tumor risks while preserving their therapeutic potential for cartilage repair.

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Publication Details

Journal
Stem Cells Translational Medicine
Published
2025-11-01
DOI
https://doi.org/10.1093/stcltm/szaf056
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
Field-Weighted Citation Impact
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article

Teratoma-free cartilage regeneration using p21 −/− iPSCs engineered with iCasp9

Derrick E. Rancourt, Roman Krawetz, Leila Larijani
Stem Cells Translational Medicine
Osteoarthritis Treatment and Mechanisms
article

Teratoma-free cartilage regeneration using p21 −/− iPSCs engineered with iCasp9

Derrick E. Rancourt, Roman Krawetz, Leila Larijani
article en

Abstract

These findings suggest that iCasp9-mediated elimination of iPSCs can effectively mitigate tumor risks while preserving their therapeutic potential for cartilage repair.

Stem Cells Translational MedicineVol. 14(11)
University of Calgary (CA), Alberta Bone and Joint Health Institute (CA)
Openalex Percentile: Top 50%
Osteoarthritis Treatment and Mechanisms
DOIOpen Access PDFOpenAlex
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Teratoma-free cartilage regeneration using <i>p21</i> −/− iPSCs engineered with iCasp9 — Derrick E. Rancourt, Roman Krawetz, et al. · Stem Cells Translational Medicine (2025) | TGRS Research Map | TGRS