Efficacy and safety of anlotinib plus EGFR-TKI for advanced non-small cell lung cancer with EGFR mutations: A meta-analysis of randomized controlled trials

Compared with EGFR-TKI monotherapy, anlotinib plus EGFR-TKI provides some clinical benefits for patients with advanced NSCLC harboring EGFR mutations, but it does not significantly improve long-term survival and has higher toxicity.

Authors

Publication Details

Journal
Medicine
Published
2025-10-31
DOI
https://doi.org/10.1097/md.0000000000045654
Primary Topic
Lung Cancer Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and safety of anlotinib plus EGFR-TKI for advanced non-small cell lung cancer with EGFR mutations: A meta-analysis of randomized controlled trials

Dailong Li, Yuan Che, Chunlai Cheng, Xiaoxi Zhang et al.
Medicine
Lung Cancer Research Studies
article

Efficacy and safety of anlotinib plus EGFR-TKI for advanced non-small cell lung cancer with EGFR mutations: A meta-analysis of randomized controlled trials

Dailong Li, Yuan Che, Chunlai Cheng, Xiaoxi Zhang, Yali Xiong, Yuan Du
article en

Abstract

Compared with EGFR-TKI monotherapy, anlotinib plus EGFR-TKI provides some clinical benefits for patients with advanced NSCLC harboring EGFR mutations, but it does not significantly improve long-term survival and has higher toxicity.

MedicineVol. 104(44)
Openalex Percentile: Top 52%
Lung Cancer Research Studies
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Efficacy and safety of anlotinib plus EGFR-TKI for advanced non-small cell lung cancer with EGFR mutations: A meta-analysis of randomized controlled trials — Dailong Li, Yuan Che, et al. · Medicine (2025) | TGRS Research Map | TGRS