Cytokine alterations in the spinal cord and serum of male rats following brachial plexus avulsion-induced neuropathic pain

These findings not only enhance our understanding of the role of cytokine signaling in the development of neuropathic pain but also suggest that targeting these signaling pathways may present a viable therapeutic strategy. By modulating cytokine activity, it might be possible to alleviate neuropathic pain in patients suffering from peripheral nerve injuries, offering a new direction for the treatment of such conditions.

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Publication Details

Journal
Medicine
Published
2025-10-31
DOI
https://doi.org/10.1097/md.0000000000045251
Primary Topic
Pain Mechanisms and Treatments
Type
article
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article

Cytokine alterations in the spinal cord and serum of male rats following brachial plexus avulsion-induced neuropathic pain

Jie Lao, Le Wang
Medicine
Pain Mechanisms and Treatments
article

Cytokine alterations in the spinal cord and serum of male rats following brachial plexus avulsion-induced neuropathic pain

Jie Lao, Le Wang
article en

Abstract

These findings not only enhance our understanding of the role of cytokine signaling in the development of neuropathic pain but also suggest that targeting these signaling pathways may present a viable therapeutic strategy. By modulating cytokine activity, it might be possible to alleviate neuropathic pain in patients suffering from peripheral nerve injuries, offering a new direction for the treatment of such conditions.

MedicineVol. 104(44)
Shanghai Jiao Tong University (CN), Fudan University (CN), Ruijin Hospital (CN), Shanghai Institute of Hematology (CN), Huashan Hospital (CN)
Openalex Percentile: Top 57%
Pain Mechanisms and Treatments
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Cytokine alterations in the spinal cord and serum of male rats following brachial plexus avulsion-induced neuropathic pain — Jie Lao, Le Wang · Medicine (2025) | TGRS Research Map | TGRS