Cytokine alterations in the spinal cord and serum of male rats following brachial plexus avulsion-induced neuropathic pain
These findings not only enhance our understanding of the role of cytokine signaling in the development of neuropathic pain but also suggest that targeting these signaling pathways may present a viable therapeutic strategy. By modulating cytokine activity, it might be possible to alleviate neuropathic pain in patients suffering from peripheral nerve injuries, offering a new direction for the treatment of such conditions.
Authors
- Jie Lao (ORCID: https://orcid.org/0000-0003-0511-3867)
- Le Wang (ORCID: https://orcid.org/0000-0002-7155-7549)
Institutions
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- Ruijin Hospital (CN)
- Shanghai Institute of Hematology (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Medicine
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1097/md.0000000000045251
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00