Cronkhite-Canada syndrome presenting with chronic diarrhea: A case report
In this case, diffuse, variably sized, densely distributed, congestive polypoid changes were seen throughout the stomach, colon, rectum, and the terminal ileum. The lesions were more pronounced in the distal region of the gastric body than in the proximal region. Histopathology was suggestive of hamartomatous polyps with infiltration by eosinophils, lymphocytes, and plasma cells. Hormonal therapy has shown significant efficacy in treating this disease. Timely therapeutic intervention combined with systematic surveillance may mitigate the potential for malignant transformation and disease-related complications.
Authors
- Junjun Wu (ORCID: https://orcid.org/0000-0002-8912-9411)
- Yufang Wang (ORCID: https://orcid.org/0000-0003-1597-3289)
- S Wu
Institutions
- Zhejiang Chinese Medical University (CN)
- Third People's Hospital of Hangzhou (CN)
Publication Details
- Journal
- Medicine
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1097/md.0000000000045458
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00