Inebilizuma treatment for acute serum AQP4 – IgG neuromyelitis optica: Case report
This case demonstrates that combination therapy with IVMP and inebilizumab during the acute phase significantly promoted visual recovery in this AQP4-IgG seropositive NMOSD patient. This finding enhances our understanding of NMOSD management. The case offers valuable clinical insights for therapeutic strategies in NMOSD. Future studies with larger cohorts are warranted to further evaluate the efficacy of the intravenous methylprednisolone pulse-inebilizumab combination in reducing relapse rates and improving long-term neurological outcomes in NMOSD.
Authors
- Peng-Fei Jiang (ORCID: https://orcid.org/0000-0002-0913-3374)
- Sheng Yang (ORCID: https://orcid.org/0000-0003-1630-8037)
- Qian Liu (ORCID: https://orcid.org/0000-0001-6595-2369)
- Shanshan Zhu (ORCID: https://orcid.org/0000-0001-9265-8595)
- Qing Chen (ORCID: https://orcid.org/0000-0002-2088-0370)
- Donghua Liu
- Bing-xin Pan
- Fang Yang (ORCID: https://orcid.org/0000-0001-7963-8418)
- Yang Shen (ORCID: https://orcid.org/0000-0003-4714-0839)
Institutions
- Quzhou City People's Hospital (CN)
- Qujiang People's Hospital (CN)
- Beijing Fengtai Hospital (CN)
Publication Details
- Journal
- Medicine
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1097/md.0000000000045293
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00