Impaired Topological Architecture of Structural Brain Networks in Obstructive Sleep Apnea: A DTI Study
Our findings show alterations in BC and NE of the SFGdor.L and BC of the SMA.L that may reflect neurobiological features of white-matter network disruption in OSA and could represent potential imaging biomarkers of early cerebral involvement. These results are correlational and longitudinal studies are needed to determine temporal relationships and causal effects.
Authors
- Xiangjun Shi (ORCID: https://orcid.org/0000-0002-3260-9676)
- Yanan Xu (ORCID: https://orcid.org/0000-0002-6747-6981)
- Ziyang Zhao (ORCID: https://orcid.org/0000-0001-7716-3439)
- Lianping Zhao (ORCID: https://orcid.org/0000-0002-1170-771X)
- Yiwei Zhao (ORCID: https://orcid.org/0000-0003-4442-2267)
- Zhijun Yao (ORCID: https://orcid.org/0000-0003-0057-0831)
- Miao Chen (ORCID: https://orcid.org/0009-0002-2686-9647)
- Wenwen Zhang (ORCID: https://orcid.org/0000-0003-1120-8977)
- Gang Huang (ORCID: https://orcid.org/0000-0002-5786-7110)
- Huiyan Zhang (ORCID: https://orcid.org/0000-0003-3406-8954)
- Jing Gao (ORCID: https://orcid.org/0009-0006-2273-8067)
- Guo Shen
Institutions
- Gansu University of Traditional Chinese Medicine (CN)
- Gansu Provincial Hospital (CN)
- Ningxia Medical University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Nature and Science of Sleep
- Published
- 2025-11-01
- DOI
- https://doi.org/10.2147/nss.s542235
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Chinese Academy of Sciences