Observation of choroidal blood flow parameters in patients with diabetic retinopathy based on ultra-widefield SS-OCTA

Choroidal hypoperfusion is a characteristic of DR. Choroidal blood flow density in patients with DR predominantly affects the medium- and large- vessel layers. The CVI shows a progressive decline as DR advances, with perfusion loss possibly initiating in the temporal subregions. Among the evaluated parameters, CVI demonstrates superior diagnostic utility over VD-CC and VD-LMVC for supporting DR diagnosis. However, all three parameters exhibit limited sensitivity in staging disease severity. CVI holds promise as a potential biomarker for monitoring DR progression.