Role of cAMP in TIR1/AFB auxin signaling: open issues

The canonical mechanism by which the phytohormone auxin regulates transcription has been one of the cornerstones of plant signaling. The recent unexpected discovery of cyclic AMP (cAMP) as a second messenger in this pathway has revised its foundations while leaving many open questions and gaps in our understanding; these will be discussed in this forum article.

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Publication Details

Journal
Trends in Plant Science
Published
2025-11-20
DOI
https://doi.org/10.1016/j.tplants.2025.10.018
Primary Topic
Plant Molecular Biology Research
Type
article
Field-Weighted Citation Impact
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article

Role of cAMP in TIR1/AFB auxin signaling: open issues

Jiřı́ Friml
Trends in Plant Science
Plant Molecular Biology Research
article

Role of cAMP in TIR1/AFB auxin signaling: open issues

Jiřı́ Friml
article en

Abstract

The canonical mechanism by which the phytohormone auxin regulates transcription has been one of the cornerstones of plant signaling. The recent unexpected discovery of cyclic AMP (cAMP) as a second messenger in this pathway has revised its foundations while leaving many open questions and gaps in our understanding; these will be discussed in this forum article.

Trends in Plant ScienceVol. 31(2)
Institute of Science and Technology Austria (AT)
Openalex Percentile: Top 74%
Plant Molecular Biology Research
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Role of cAMP in TIR1/AFB auxin signaling: open issues — Jiřı́ Friml · Trends in Plant Science (2025) | TGRS Research Map | TGRS