Reactive astrocyte-related pathogenic genes in depression: A multi-omics Mendelian randomization study

Our study elucidated the potential involvement of reactive astrocyte-related genes, especially LGALS3, PDGFA, and GCDH.

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Publication Details

Journal
Journal of Affective Disorders
Published
2025-11-20
DOI
https://doi.org/10.1016/j.jad.2025.120706
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Reactive astrocyte-related pathogenic genes in depression: A multi-omics Mendelian randomization study

Shaobin Jia, Linsun Lin, Rui Wang, Yingying Li et al.
Journal of Affective Disorders
Tryptophan and brain disorders
article

Reactive astrocyte-related pathogenic genes in depression: A multi-omics Mendelian randomization study

Shaobin Jia, Linsun Lin, Rui Wang, Yingying Li, Tao Wang, Ziyi Guo, Hetian Sun, Peigang Fang, Min Chen
article en

Abstract

Our study elucidated the potential involvement of reactive astrocyte-related genes, especially LGALS3, PDGFA, and GCDH.

Journal of Affective DisordersVol. 395(Pt A)
Macau University of Science and Technology (MO), Anhui Medical University (CN), Anhui University of Traditional Chinese Medicine (CN), Second Affiliated Hospital of Anhui Medical University (CN)
Openalex Percentile: Top 64%
Tryptophan and brain disorders
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