COMPARATIVE EVALUATION OF INTRAVENOUS INDOCYANINE GREEN DYE FOR ASSESSMENT OF BILIARY ANATOMY AND TO ASSESS COMPLICATIONS IN LAPAROSCOPIC CHOLECYSTECTOMY: A PROSPECTIVE STUDY

Background: laparoscopic cholecystectomy (LC) is commonly performed operative procedure to remove gall bladder stones. Fluorescenceenhanced IOC using indocyanine green (ICG) dye offers real-time visualization without radiation exposure and may improve operative safety. Aim: To compare outcomes of laparoscopic cholecystectomy performed with and without use of ICG dye in terms of biliary visualization, intraoperative complications, and postoperative recovery. Methods: A prospective comparative study was conducted on 120 patients with symptomatic cholelithiasis undergoing LC at SMIMER Hospital, Surat. Patients were randomized into two groups: Group A(ICG, n=60) received 2.5 mg ICG intravenously 45 minutes preoperatively, and Group B (non-ICG, n=60) underwent conventional laparoscopic cholecystectomy. Parameters analyzed included biliary visualization, detection of CBD stones, complications, and hospital stay. Statistical analysis was performed using SPSS v25, with p < 0.05 considered signicant. Results: CBD visualization was signicantly higher with ICG (96%) compared to non-ICG (87%, p=0.04). The cystic duct–CBD junction was more clearly dened with ICG (94% vs 82%, p=0.02). No bile duct injuries occurred in the ICG group, while three (5%) occurred in non-ICG patients. Mean hospital stay was shorter with ICG (3.6 days vs 4.4 days, p=0.02). Conclusion: ICGassisted uorescence cholangiography enhances biliary anatomy visualization and may reduce complications and recovery time. It is a safe, effective, and radiation-free adjunct to standard laparoscopic cholecystectomy.

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Journal
INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
Published
2025-11-01
DOI
https://doi.org/10.36106/ijsr/8510105
Primary Topic
Gallbladder and Bile Duct Disorders
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article
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article

COMPARATIVE EVALUATION OF INTRAVENOUS INDOCYANINE GREEN DYE FOR ASSESSMENT OF BILIARY ANATOMY AND TO ASSESS COMPLICATIONS IN LAPAROSCOPIC CHOLECYSTECTOMY: A PROSPECTIVE STUDY

Rajesh Chandnani, Mudit Maheshwari, Yogesh Modi
INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
Gallbladder and Bile Duct Disorders
article

COMPARATIVE EVALUATION OF INTRAVENOUS INDOCYANINE GREEN DYE FOR ASSESSMENT OF BILIARY ANATOMY AND TO ASSESS COMPLICATIONS IN LAPAROSCOPIC CHOLECYSTECTOMY: A PROSPECTIVE STUDY

Rajesh Chandnani, Mudit Maheshwari, Yogesh Modi
article en

Abstract

Background: laparoscopic cholecystectomy (LC) is commonly performed operative procedure to remove gall bladder stones. Fluorescenceenhanced IOC using indocyanine green (ICG) dye offers real-time visualization without radiation exposure and may improve operative safety. Aim: To compare outcomes of laparoscopic cholecystectomy performed with and without use of ICG dye in terms of biliary visualization, intraoperative complications, and postoperative recovery. Methods: A prospective comparative study was conducted on 120 patients with symptomatic cholelithiasis undergoing LC at SMIMER Hospital, Surat. Patients were randomized into two groups: Group A(ICG, n=60) received 2.5 mg ICG intravenously 45 minutes preoperatively, and Group B (non-ICG, n=60) underwent conventional laparoscopic cholecystectomy. Parameters analyzed included biliary visualization, detection of CBD stones, complications, and hospital stay. Statistical analysis was performed using SPSS v25, with p < 0.05 considered signicant. Results: CBD visualization was signicantly higher with ICG (96%) compared to non-ICG (87%, p=0.04). The cystic duct–CBD junction was more clearly dened with ICG (94% vs 82%, p=0.02). No bile duct injuries occurred in the ICG group, while three (5%) occurred in non-ICG patients. Mean hospital stay was shorter with ICG (3.6 days vs 4.4 days, p=0.02). Conclusion: ICGassisted uorescence cholangiography enhances biliary anatomy visualization and may reduce complications and recovery time. It is a safe, effective, and radiation-free adjunct to standard laparoscopic cholecystectomy.

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
Sardar Vallabhbhai National Institute of Technology Surat (IN)
Openalex Percentile: Top 50%
Gallbladder and Bile Duct Disorders
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COMPARATIVE EVALUATION OF INTRAVENOUS INDOCYANINE GREEN DYE FOR ASSESSMENT OF BILIARY ANATOMY AND TO ASSESS COMPLICATIONS IN LAPAROSCOPIC CHOLECYSTECTOMY: A PROSPECTIVE STUDY — Rajesh Chandnani, Mudit Maheshwari, et al. · INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH (2025) | TGRS Research Map | TGRS