SCHIFF BASE COMPLEXES OF CO(II) AND NI(II) DERIVED FROM 2- AMINOPYRIMIDINE AND 2-HYDROXYNAPHTHALDEHYDE: SYNTHESIS, SPECTRAL CHARACTERIZATION, AND BIOLOGICAL SIGNIFICANCE

A new series of Co(II), Ni(II) complexes of tridentate Schiff base derived from condensation of 2-aminopyrimidine with 2- hydroxynaphthaldehyde were synthesized in a 2:1 molar ratio. Physical (magnetic measurements, molar conductance), spectral (IR, UV-Vis and Mass) and analytical data have established the structures of synthesized Schiff base and its metal complexes. The elemental analysis data suggest the stoichiometry to be 2:1 (L: M). Infra-red spectral data indicate the coordination between the ligand and the central metal ion through deprotonated phenolic oxygen, pyrimidine nitrogen and azomethine nitrogen atoms. Spectral studies and magnetic susceptibility measurements suggest an octahedral geometry for the complexes. The ligand and its complexes were tested / screened for their antibacterial activity against two Gram-positive bacteria species Staphylococcus aureus and Lactobacillus and two Gram-negative species Escherichia coli and Pseudomonas aeruginosa. It is observed that the ligand as well as the complexes showed good activity against all microbes.