Relationship between the preoperative AST/ALT ratio and postoperative delirium and 3-year mortality in patients undergoing total knee or hip arthroplasty: a prospective cohort study
Preoperative elevation of the serum AST/ALT ratio is a potential risk factor for POD, and its effect may be partially mediated by AD-related CSF biomarkers. However, an increase in the AST/ALT ratio did not have a significant effect on the three-year survival rate of POD patients.
Authors
- Jian Kong (ORCID: https://orcid.org/0000-0002-2872-2078)
- Shanling Xu (ORCID: https://orcid.org/0000-0002-1801-1440)
- Jiahan Wang (ORCID: https://orcid.org/0009-0006-5115-6939)
- Rui Dong (ORCID: https://orcid.org/0000-0001-8591-0828)
- Bin Wang (ORCID: https://orcid.org/0000-0002-9945-1818)
- Chuan Li (ORCID: https://orcid.org/0000-0002-5612-522X)
- Yanan Lin
- Yanlin Bi (ORCID: https://orcid.org/0000-0002-7130-1885)
- Yuanlong Wang (ORCID: https://orcid.org/0000-0001-9196-3555)
- Shuhui Hua
- Xu Lin (ORCID: https://orcid.org/0009-0007-4097-2006)
- Hongyan Gong
Institutions
- Qingdao University (CN)
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1097/js9.0000000000003914
- Citations
- 1
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.55