Corneal Transplant Failure Is Associated With a High Percentage of Epithelial Downgrowth: A 24-Year Retrospective Clinical and Histological Study From a Single Academic Institute

EDG is diagnostically complex, and many suggestive features on pathology are not definitive. The frequency of cases with clinical suspicion for EDG and/or histopathologic features raising consideration of EDG have increased over a 24-year period. This study underscores the need for further research to aid in definitive diagnosis of EDG.

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Publication Details

Journal
Cornea
Published
2025-09-25
DOI
https://doi.org/10.1097/ico.0000000000003990
Primary Topic
Corneal surgery and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Corneal Transplant Failure Is Associated With a High Percentage of Epithelial Downgrowth: A 24-Year Retrospective Clinical and Histological Study From a Single Academic Institute

Hillary C. Stiefel, David John Wilson, Daniel M. Albert, Winston Chamberlain et al.
Cornea
Corneal surgery and disorders
article

Corneal Transplant Failure Is Associated With a High Percentage of Epithelial Downgrowth: A 24-Year Retrospective Clinical and Histological Study From a Single Academic Institute

Hillary C. Stiefel, David John Wilson, Daniel M. Albert, Winston Chamberlain, Radwa Elsharawi, J Kałuzny
article en

Abstract

EDG is diagnostically complex, and many suggestive features on pathology are not definitive. The frequency of cases with clinical suspicion for EDG and/or histopathologic features raising consideration of EDG have increased over a 24-year period. This study underscores the need for further research to aid in definitive diagnosis of EDG.

CorneaVol. 45(1)
Oregon Health & Science University (US)
Openalex Percentile: Top 50%
Corneal surgery and disorders
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