Postoperative delirium and delayed neurocognitive recovery in older adults with prior coronavirus disease: a prospective cohort study

Prior SARS-CoV-2 infection was independently associated with an increased risk of POD, which was potentially mediated by APSP. In contrast, no significant association was observed between prior COVID-19 and DNR incidence. In addition, full COVID-19 vaccination significantly reduced the risk of POD, suggesting that perioperative COVID-19 vaccine promotion is a potential public health strategy for improving the prognosis of the elderly.

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Publication Details

Journal
International Journal of Surgery
Published
2025-11-11
DOI
https://doi.org/10.1097/js9.0000000000003975
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
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0.00
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article

Postoperative delirium and delayed neurocognitive recovery in older adults with prior coronavirus disease: a prospective cohort study

Ying Tong, Kaile Cui, Shaoqiong Zhang, Bo Fang et al.
International Journal of Surgery
Intensive Care Unit Cognitive Disorders
article

Postoperative delirium and delayed neurocognitive recovery in older adults with prior coronavirus disease: a prospective cohort study

Ying Tong, Kaile Cui, Shaoqiong Zhang, Bo Fang, Yuan Li, Xin Liang, Xingen Yao
article en

Abstract

Prior SARS-CoV-2 infection was independently associated with an increased risk of POD, which was potentially mediated by APSP. In contrast, no significant association was observed between prior COVID-19 and DNR incidence. In addition, full COVID-19 vaccination significantly reduced the risk of POD, suggesting that perioperative COVID-19 vaccine promotion is a potential public health strategy for improving the prognosis of the elderly.

International Journal of SurgeryVol. 112(2)
General Hospital of Shenyang Military Region (CN), First Hospital of China Medical University (CN), China Medical University (CN)
Openalex Percentile: Top 59%
Intensive Care Unit Cognitive Disorders
DOIOpen Access PDFOpenAlex
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Postoperative delirium and delayed neurocognitive recovery in older adults with prior coronavirus disease: a prospective cohort study — Ying Tong, Kaile Cui, et al. · International Journal of Surgery (2025) | TGRS Research Map | TGRS