Regenerating islet derived Family Member 4 (REG4) does not influence parameters of hemostasis in colorectal cancer
Extensive in vitro and microfluidic methods showed no effect of REG4 on coagulation parameters in CRC. Further research is needed into the mechanism behind CAT, as its understanding will help in better risk prediction and treatment.
Authors
- Rayna J.S. Anijs (ORCID: https://orcid.org/0000-0002-4936-0256)
- Suzanne C. Cannegieter (ORCID: https://orcid.org/0000-0003-4707-2303)
- E.H. Laghmani
- Henri H. Versteeg (ORCID: https://orcid.org/0000-0003-4294-175X)
- Jeroen T. Buijs (ORCID: https://orcid.org/0000-0001-5816-9739)
- Yen Nhi Nguyen
- Araci M. R. Rondon (ORCID: https://orcid.org/0000-0002-2703-8805)
- Betül Ünlü (ORCID: https://orcid.org/0000-0001-5587-4176)
- Monika Yanovska
- Ruud van den Akker
Institutions
- Leiden University Medical Center (NL)
Publication Details
- Journal
- Thrombosis Research
- Published
- 2025-11-09
- DOI
- https://doi.org/10.1016/j.thromres.2025.109535
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00