The expression of Mutl Protein Homolog 1 (MLH1) and Muts Homolog 2 (MSH2) in colorectal carcinoma: An immunohistochemical study
IHC test for detection of MLH1 and MSH2 expression represents a rapid, reliable, and cost-effective method to detect MMR deficiency in CRC tumors. Expression of MMR protein demonstrated significant association with grade of tumor, stage of tumor, lymphovascular invasion, and lymph node status.
Authors
- Manisha Sharma (ORCID: https://orcid.org/0000-0001-6282-4847)
- Karamjit S. Gill
- Gurleen Kaur (ORCID: https://orcid.org/0000-0002-2710-3654)
- Manas Madan
- Ishaan Khanna
- Eshita Garg
Institutions
- Government Medical College, Amritsar (IN)
Publication Details
- Journal
- Indian Journal of Pathology and Microbiology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.4103/ijpm.ijpm_538_24
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00