Characterization and genetic modification of <i>Pseudomonas chlororaphis</i> DZ15 with high yield of phenazine-1-carboxylic acid
Our study firstly investigated the genomic characteristics of wild-type strain with the highest PCA production (i.e. P. chlororaphis DZ15) through whole-genome sequencing analysis. Then, our results indicated that the high expression level of phz cluster promoter and physiological characteristics of P. chlororaphis DZ15 both contributed to its high PCA production. Furthermore, PCA production in P. chlororaphis DZ15 was enhanced through genetic modification.
Authors
- Sheng‐Jie Yue (ORCID: https://orcid.org/0000-0002-6283-5893)
- Jing Wang (ORCID: https://orcid.org/0000-0002-6326-4869)
- Yan‐Fang Nie
- Peng Huang (ORCID: https://orcid.org/0000-0002-1710-3378)
- Qi Zhu (ORCID: https://orcid.org/0000-0003-3965-8419)
- J. S. Huang (ORCID: https://orcid.org/0000-0002-4935-8551)
- Hongbo Hu (ORCID: https://orcid.org/0009-0005-3944-8325)
- Xuehong Zhang
Institutions
- East China University of Science and Technology (CN)
- Shanghai Jiao Tong University (CN)
- University College London (GB)
- Jiangxi Normal University (CN)
Publication Details
- Journal
- Journal of Applied Microbiology
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1093/jambio/lxaf269
- Citations
- 1
- Primary Topic
- Bacterial Genetics and Biotechnology
- Type
- article
- Field-Weighted Citation Impact
- 1.82