Obesity, aldosterone, and natriuretic peptides in patients with heart failure and reduced ejection fraction
Greater adiposity was associated with higher concentrations of aldosterone but lower levels of B-type natriuretic peptides in patients with HFrEF. Adipose tissue may influence the neurohumoral milieu in HFrEF, including the secretion of aldosterone.
Authors
- Shingo Matsumoto (ORCID: https://orcid.org/0000-0003-2698-0839)
- Kieran F. Docherty (ORCID: https://orcid.org/0000-0002-5446-9969)
- Pardeep S. Jhund (ORCID: https://orcid.org/0000-0003-4306-5317)
- John J.V. McMurray (ORCID: https://orcid.org/0000-0002-6317-3975)
- Lars Køber (ORCID: https://orcid.org/0000-0002-6635-1466)
- Jawad H. Butt (ORCID: https://orcid.org/0000-0002-7380-4144)
- Milton Packer (ORCID: https://orcid.org/0000-0003-1828-2387)
- Jean-Lucien Rouleau (ORCID: https://orcid.org/0000-0002-5353-3877)
- Muthiah Vaduganathan (ORCID: https://orcid.org/0000-0003-0885-1953)
- Akshay S. Desai (ORCID: https://orcid.org/0000-0002-1443-0701)
- William T Abraham
- Scott Solomon
Institutions
- Brigham and Women's Hospital (US)
- Toho University (JP)
- Montreal Heart Institute (CA)
- Baylor University Medical Center (US)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- British Heart Foundation (GB)
- Zealand University Hospital (DK)
- The Ohio State University (US)
- Université de Montréal (CA)
- University of Glasgow (GB)
Publication Details
- Journal
- Cardiovascular Research
- Published
- 2025-11-15
- DOI
- https://doi.org/10.1093/cvr/cvaf235
- Citations
- 1
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.39