Transbronchial Cryoablation for Early‐Stage Non‐Small Cell Lung Cancer of the Central Airway Complicated by Idiopathic Pulmonary Fibrosis

Interstitial lung disease presents significant challenges in managing early-stage non-small cell lung cancer due to the high risk of acute exacerbation with standard therapies. We report the case of an 82-year-old man with idiopathic pulmonary fibrosis and central airway squamous cell carcinoma who was treated with transbronchial cryoablation. The procedure was completed without major complications, and no tumour recurrence was observed over an 11-month follow-up. This case highlights the potential of transbronchial cryoablation as a feasible local treatment option for early-stage non-small cell lung cancer in patients with idiopathic pulmonary fibrosis, offering a safer alternative to surgery or radiation therapy.

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Publication Details

Journal
Respirology Case Reports
Published
2025-11-01
DOI
https://doi.org/10.1002/rcr2.70408
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Transbronchial Cryoablation for Early‐Stage Non‐Small Cell Lung Cancer of the Central Airway Complicated by Idiopathic Pulmonary Fibrosis

Takashi Niwa, Masamitsu Hamakawa, Toshihide Yokoyama, Tadashi Ishida et al.
Respirology Case Reports
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Transbronchial Cryoablation for Early‐Stage Non‐Small Cell Lung Cancer of the Central Airway Complicated by Idiopathic Pulmonary Fibrosis

Takashi Niwa, Masamitsu Hamakawa, Toshihide Yokoyama, Tadashi Ishida, Yasushi Fukuda, Ryoju Sato
article en

Abstract

Interstitial lung disease presents significant challenges in managing early-stage non-small cell lung cancer due to the high risk of acute exacerbation with standard therapies. We report the case of an 82-year-old man with idiopathic pulmonary fibrosis and central airway squamous cell carcinoma who was treated with transbronchial cryoablation. The procedure was completed without major complications, and no tumour recurrence was observed over an 11-month follow-up. This case highlights the potential of transbronchial cryoablation as a feasible local treatment option for early-stage non-small cell lung cancer in patients with idiopathic pulmonary fibrosis, offering a safer alternative to surgery or radiation therapy.

Respirology Case ReportsVol. 13(11)
Kurashiki Central Hospital (JP), Kanagawa Cardiovascular and Respiratory Center (JP)
Forskningsrådet om Hälsa, Arbetsliv och Välfärd
Openalex Percentile: Top 50%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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Transbronchial Cryoablation for Early‐Stage Non‐Small Cell Lung Cancer of the Central Airway Complicated by Idiopathic Pulmonary Fibrosis — Takashi Niwa, Masamitsu Hamakawa, et al. · Respirology Case Reports (2025) | TGRS Research Map | TGRS