Integrating AI into the Clinical Workflows Across the Cancer Care Continuum: Opportunities and Challenges

Cancer cases are projected to hit 35 million worldwide by 2050, posing a significant burden on health care systems. The cancer care continuum has evolved to precision medicine practices, provisioning personalized treatments based on multimodal and multiomics data. Contextual analysis of such diverse, voluminous, spatiotemporal patient data is beyond human cognitive capacity. Artificial Intelligence (AI) technologies are reshaping the data mining paradigm in healthcare by delivering novel data-led insights in real time. AI-based methods for cancer risk predictions, diagnosis, prognosis, and therapeutics are developed, validated, and approved, indicating readiness for integration in clinical workflows. Additional validation of AI models using real-world data representing diverse populations is recommended to address clinical, technical, regulatory, ethical, and legal challenges, along with trust issues. Integrating AI tools into cancer care workflows to augment clinical decision-making, without compromising clinical autonomy and patient safety, is essential to address the increasing demand for cancer care by 2050.

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Publication Details

Journal
The Cancer Journal
Published
2025-11-01
DOI
https://doi.org/10.1097/ppo.0000000000000799
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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article

Integrating AI into the Clinical Workflows Across the Cancer Care Continuum: Opportunities and Challenges

Urmila Kulkarni Kale, Gorkey Vemulapalli
The Cancer Journal
Artificial Intelligence in Healthcare and Education
article

Integrating AI into the Clinical Workflows Across the Cancer Care Continuum: Opportunities and Challenges

Urmila Kulkarni Kale, Gorkey Vemulapalli
article en

Abstract

Cancer cases are projected to hit 35 million worldwide by 2050, posing a significant burden on health care systems. The cancer care continuum has evolved to precision medicine practices, provisioning personalized treatments based on multimodal and multiomics data. Contextual analysis of such diverse, voluminous, spatiotemporal patient data is beyond human cognitive capacity. Artificial Intelligence (AI) technologies are reshaping the data mining paradigm in healthcare by delivering novel data-led insights in real time. AI-based methods for cancer risk predictions, diagnosis, prognosis, and therapeutics are developed, validated, and approved, indicating readiness for integration in clinical workflows. Additional validation of AI models using real-world data representing diverse populations is recommended to address clinical, technical, regulatory, ethical, and legal challenges, along with trust issues. Integrating AI tools into cancer care workflows to augment clinical decision-making, without compromising clinical autonomy and patient safety, is essential to address the increasing demand for cancer care by 2050.

The Cancer JournalVol. 31(6)
City of Hope (US), Precision for Medicine (United States) (US), Citadel (US)
Openalex Percentile: Top 72%
Artificial Intelligence in Healthcare and Education
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