Thymosin α1 Elevates Lymphocyte Counts and Improves Immunoradiotherapy Outcomes in Patients with Advanced Cancer

A 7-day loading dose of Tα1 elevated lymphocyte counts in advanced cancer patients and was accompanied by satisfactory safety and efficacy profiles. It should be noted that the median follow-up of 13.7 months may be insufficient to fully assess long-term survival outcomes and the potential for late-onset toxicities. As this was an exploratory analysis across multiple tumor types, these findings warrant validation in larger, randomized studies with more homogenous cohorts.

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Publication Details

Journal
Cancer Management and Research
Published
2025-11-01
DOI
https://doi.org/10.2147/cmar.s555975
Primary Topic
Cellular Mechanics and Interactions
Type
article
Field-Weighted Citation Impact
0.00
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article

Thymosin α1 Elevates Lymphocyte Counts and Improves Immunoradiotherapy Outcomes in Patients with Advanced Cancer

Pengfei Xing, Rongzheng Chen, Liyuan Zhang, Junjun Zhang et al.
Cancer Management and Research
Cellular Mechanics and Interactions
article

Thymosin α1 Elevates Lymphocyte Counts and Improves Immunoradiotherapy Outcomes in Patients with Advanced Cancer

Pengfei Xing, Rongzheng Chen, Liyuan Zhang, Junjun Zhang, Meiling Xu, Xiangrong Zhao, Yuehong Kong
article en

Abstract

A 7-day loading dose of Tα1 elevated lymphocyte counts in advanced cancer patients and was accompanied by satisfactory safety and efficacy profiles. It should be noted that the median follow-up of 13.7 months may be insufficient to fully assess long-term survival outcomes and the potential for late-onset toxicities. As this was an exploratory analysis across multiple tumor types, these findings warrant validation in larger, randomized studies with more homogenous cohorts.

Cancer Management and ResearchVol. Volume 17
Soochow University (CN), Second Affiliated Hospital of Soochow University (CN)
Openalex Percentile: Top 64%
Cellular Mechanics and Interactions
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