Integrative Multi-Omics and Functional Validation Reveal the Role of the TACE Refractoriness-Associated Gene ATP1B3 in Hepatocellular Carcinoma
This study identifies TACE refractoriness-related gene ATP1B3 as a key regulator of tumor progression, immune evasion, and therapeutic resistance in HCC. These findings highlight ATP1B3 as a promising biomarker for patient stratification and a potential therapeutic target to improve clinical outcomes in HCC.
Authors
- Qiaoyou Weng (ORCID: https://orcid.org/0000-0003-0023-4598)
- Qingqing Wu (ORCID: https://orcid.org/0000-0002-8931-3630)
- Min Xu (ORCID: https://orcid.org/0000-0002-6661-5177)
- Feng Chen (ORCID: https://orcid.org/0000-0003-4402-4955)
- Cong Zhang (ORCID: https://orcid.org/0009-0009-7547-5119)
- Hui Meng
- Qin Hu (ORCID: https://orcid.org/0000-0003-2568-0754)
- Yang Yang
- Lulu Zeng
- Liyun Zheng
- Rongfang Qiu (ORCID: https://orcid.org/0000-0002-4945-2345)
- Minjiang Chen
- Zhongwei Zhao
- Jiansong Ji (ORCID: https://orcid.org/0009-0006-8018-2757)
Institutions
- Ningbo University (CN)
- Lishui University (CN)
- Lishui Central Hospital (CN)
- Lishui City People's Hospital (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Journal of Hepatocellular Carcinoma
- Published
- 2025-11-01
- DOI
- https://doi.org/10.2147/jhc.s537990
- Citations
- 1
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.32