Comparative Effectiveness of Pharmacological, Non-Pharmacological, and Combined Strategies for Pain Relief During Colonoscopy: A Bayesian Network Meta-Analysis of Randomized Trials
Multimodal strategies that combine pharmacological agents, especially pethidine or propofol, with non-pharmacological techniques such as CO<sub>2</sub> insufflation and water perfusion provide the most effective pain relief during colonoscopy.
Authors
- Lifan Xu
- Lei Shi (ORCID: https://orcid.org/0000-0001-5709-6515)
- Min-hong Cai
- Shan Tian (ORCID: https://orcid.org/0009-0005-5414-0353)
- Fanfu Fang (ORCID: https://orcid.org/0000-0001-7535-5242)
- Xiaonan Huang (ORCID: https://orcid.org/0009-0003-9126-7391)
- Tingting Mai (ORCID: https://orcid.org/0009-0006-7886-3465)
- Jie Chen (ORCID: https://orcid.org/0000-0003-2780-5426)
- Hao Wang (ORCID: https://orcid.org/0000-0001-9990-2714)
- Han Wang (ORCID: https://orcid.org/0000-0001-9845-7436)
Institutions
- University of Shanghai for Science and Technology (CN)
- Second Military Medical University (CN)
- Shanghai Medical Information Center (CN)
- Changhai Hospital (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2025-11-01
- DOI
- https://doi.org/10.2147/jpr.s554665
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Health Commission of the People's Republic of China
- National Key Research and Development Program of China