Component compatibility of Yinchenhao decoction attenuates high-fat diet-induced metabolic-associated steatotic liver disease in mice
The combination of geniposide (200 mg/kg), chlorogenic acid (160 mg/kg), and rhubarb polysaccharide (340 mg/kg) exerts the optimal ameliorative effect on MASLD in mice. This superior efficacy is presumably achieved by synergistically regulating the key nodes of glycolipid metabolism and bile acid metabolism, ultimately optimizing the therapeutic outcome.
Authors
- Y. Gao (ORCID: https://orcid.org/0000-0001-6326-4773)
- Xiaobing Dou (ORCID: https://orcid.org/0000-0002-2465-3079)
- Jiannan Qiu (ORCID: https://orcid.org/0000-0002-6736-7224)
- Chen Lin (ORCID: https://orcid.org/0000-0002-2275-997X)
- Fangying Xu (ORCID: https://orcid.org/0000-0001-6074-3234)
- Rui Xue
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Journal of Zhejiang University (Medical Sciences)
- Published
- 2025-11-01
- DOI
- https://doi.org/10.3724/zdxbyxb-2025-0323
- Primary Topic
- Saffron Plant Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China