Caught in the Act: Tumor-Immune Interactions in Circulation of Patients with Immune Marker Positive Circulating Tumor Cells
These findings support membrane transfer as a potential mechanism for the acquisition of immune markers by CTCs and LEVs and provide in vivo evidence of contact-dependent tumor-immune interactions in circulation with implications for immune modulation and clinical interpretation of the im.CTC phenotype.
Authors
- Peter Kühn (ORCID: https://orcid.org/0000-0003-2629-4505)
- Valerie Hennes
- Amin Naghdloo (ORCID: https://orcid.org/0009-0009-4824-3320)
- James Hicks (ORCID: https://orcid.org/0000-0001-5353-4338)
- Dean Tessone (ORCID: https://orcid.org/0009-0006-0190-9613)
- Mohamed Kamal (ORCID: https://orcid.org/0000-0001-8663-8846)
Institutions
- University of Southern California (US)
- USC Norris Comprehensive Cancer Center (US)
- Convergent Science (United States) (US)
Publication Details
- Journal
- Cancers
- Published
- 2025-11-15
- DOI
- https://doi.org/10.3390/cancers17223667
- Citations
- 1
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 1.62
Funders
- Cedars-Sinai Medical Center