The impact of the eosinophil on the risk of acute exacerbation in asthma patients
In this first nationwide, propensity-matched cohort exceeding 100 000 adults, elevated blood eosinophil counts independently predicted both short-term and long-term moderate-to-severe asthma exacerbations across all age and sex strata. Peak eosinophil measurement thus offers a practical biomarker for early identification of high-risk patients who may benefit from intensified anti-eosinophilic or inhaled corticosteroid/long-acting beta agonist-based strategies.
Authors
- Cheng‐Yi Wang (ORCID: https://orcid.org/0000-0001-7426-0743)
- Hao‐Chien Wang (ORCID: https://orcid.org/0000-0002-7528-7494)
- Chao‐Hsien Chen (ORCID: https://orcid.org/0000-0002-2176-3504)
- Yahui Wang (ORCID: https://orcid.org/0000-0001-6645-8485)
Institutions
- Fu Jen Catholic University (TW)
- National Sun Yat-sen University (TW)
- National Taiwan University (TW)
- Mackay Memorial Hospital (TW)
- Mackay Medical University (TW)
- Chi Mei Medical Center (TW)
- Cardinal Tien Hospital (TW)
Publication Details
- Journal
- BMJ Open Respiratory Research
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1136/bmjresp-2024-003129
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00