Genome‐Wide Meta‐Analysis of Parkinson's Disease Associated Genetic Loci and Validation of Therapeutic Targets
Through genome-wide meta-analysis, MR, colocalization, and PheWAS, we identified genetic loci associated with PD and assessed GCLC and GFPT1 as potential therapeutic targets.
Authors
- Xinling Yang (ORCID: https://orcid.org/0000-0002-4517-0500)
- Shan Yang (ORCID: https://orcid.org/0000-0002-3564-5111)
- Qinfen Wu (ORCID: https://orcid.org/0000-0003-1360-3313)
Institutions
- Xinjiang Medical University (CN)
- Second Affiliated Hospital of Xinjiang Medical University (CN)
- Xinjiang University (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/brb3.71087
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- AstraZeneca