Berberine ameliorates high-fat diet-induced metabolic disorders through promoting gut Akkermansia and modulating bile acid metabolism
Berberine, through Akkermansia, maintains intestinal integrity and reduces cholesterol, highlighting its potential as a therapeutic agent for metabolic disorders. Combining berberine with Akkermansia enhances its efficacy against hyperlipidemia.
Authors
- Weijian Hang (ORCID: https://orcid.org/0000-0002-7277-2929)
- Xiaofeng Kang (ORCID: https://orcid.org/0000-0002-2724-326X)
- Juan Chen (ORCID: https://orcid.org/0000-0001-5801-9124)
- Lu He (ORCID: https://orcid.org/0000-0002-7367-2452)
- Xuan Cao
- Rui Yin (ORCID: https://orcid.org/0009-0006-0496-8440)
Institutions
- University of Toronto (CA)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-11-16
- DOI
- https://doi.org/10.1186/s13020-025-01251-6
- Primary Topic
- Berberine and alkaloids research
- Type
- article
- Field-Weighted Citation Impact
- 0.00